Catch and release: 14-3-3 controls Ncd in meiotic spindles
نویسنده
چکیده
During Drosophila melanogaster oogenesis, spindle assembly occurs without centrosomes and relies on signals from chromosomes. Beaven et al. (2017. J. Cell. Biol. https://doi.org/10.1083/jcb.201704120) show that 14-3-3 proteins bind and inhibit a key microtubule motor, Ncd, during oogenesis, but Aurora B releases Ncd inhibition near chromosomes, allowing Ncd to work in the right time and place.
منابع مشابه
14-3-3 regulation of Ncd reveals a new mechanism for targeting proteins to the spindle in oocytes
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