Inhibitory Effects of Crude α-Mangostin, a Xanthone Derivative, on Two Different Categories of Colon Preneoplastic Lesions Induced by 1, 2-dimethylhydrazine in the Rat

In recent decades, there has been increasing interest in the use of herbs to maintain human health, many growing in the Southern and Eastern Asian countries. One example, pericarps of Garcinia mangostana (GM), called mangosteen, have been in use for hundreds of years as a traditional herbal medicine for a variety of purposes, including treatment of skin infections and wounds (Mahabusarakam, 1987), or malaria infections (Likhitwitayawuid et al., 1998). Investigators have recently focused on the medical properties Inhibitory Effects of Crude α-Mangostin, a Xanthone Derivative, on Two Different Categories of Colon Preneoplastic Lesions Induced by 1, 2-dimethylhydrazine in the Rat