Drusen Imaging: A Review

نویسندگان

  • Allan A. Hunter
  • Eric K. Chin
  • David R.P. Almeida
  • David G. Telander
چکیده

Drusen represent the hallmark of non-exudative age-related macular degeneration (AMD). Drusen vary in their location within the retina, ranging from sub-retinal pigment epithelium (RPE) drusen and sub-neurosensory retinal drusenoid deposits above the RPE (or pseudo-drusen). In this paper, we review the rapidly advancing imaging techniques currently available to better correlate drusen volume to clinical stage. This includes, but is not limited to, fundus photography, fluorescein angiography, optical coherence tomography, infrared imaging, fundus autofluorescence, confocal adaptive-optics imaging, and hyperspectral retinal imaging. A new understanding of drusen role in the pathogenesis of the disease may be possible with these imaging modalities in future clinical studies.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Drusen and Sub Retinal Drusenoid Deposits ( SDD ) in Age Related Macular Degeneration

Purpose: To review drusen and sub retinal drusenoid deposits in age related macular degeneration as regards their pathogenesis, morphology, differentiation and their importance as regards the visual prognosis of age related macular degeneration (AMD). Results: Each type of drusen or drusenoid deposits has a different visual prognosis, and the differentiation of them using multimodal imaging tes...

متن کامل

Imaging Methods in the Diagnosis of Optic Disc Drusen

Optic disc drusen (ODD) are benign congenital anomalies of the optic nerve characterized by calcified hyaline bodies. While superficial drusen can be diagnosed easily during fundus examination, detecting buried drusen requires the use of additional imaging methods such as B-scan ultrasonography (USG), fundus fluorescein angiography (FFA), computed tomography (CT) and fundus autofluorescence (FA...

متن کامل

Photoreceptor layer thinning over drusen in eyes with age-related macular degeneration imaged in vivo with spectral-domain optical coherence tomography.

PURPOSE Detect changes in the neurosensory retina using spectral-domain optical coherence tomography (SD OCT) imaging over drusen in age-related macular degeneration (AMD). Quantitative imaging biomarkers may aid in defining risk of disease progression. DESIGN Cross-sectional, case-control study evaluating SD OCT testing in AMD. PARTICIPANTS AND CONTROLS Seventeen eyes of 12 subjects with n...

متن کامل

Spectral domain optical coherence tomography imaging of dry age-related macular degeneration.

Spectral domain optical coherence tomography is a useful new technology for imaging and measuring geographic atrophy (GA) and drusen, the hallmarks of dry age-related macular degeneration (AMD). The advantage of using this novel technique over other imaging modalities for dry AMD is that the same scan pattern can be used to image both drusen and GA while obtaining reproducible, quantitative dat...

متن کامل

Autofluorescence distribution associated with drusen in age-related macular degeneration.

PURPOSE To determine whether drusen in patients with age-related maculopathy and macular degeneration (ARM/AMD) are associated with focal changes in retinal pigment epithelium (RPE) lipofuscin fluorescence. METHOD A new autofluorescence imaging device was used to study lipofuscin distribution associated with individual drusen in 20 patients with ARM/AMD. Paired monochromatic and autofluoresce...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014