Rodent Models for Metabolic Syndrome Research

P-214: Testosterone to Induce Mice Models for The Study of Polycystic Ovary Syndrome

Background: Polycystic ovary syndrome (PCOS) is one of the most common causes of anovulation, infertility and hyperandrogenism in women, affecting 5-10% of women of reproductive age. Due to the ethical limitations on human experimentation, appropriate animal models that mimic many or all PCOS characteristics would facilitate research leading to improved understanding of the pathogenesis of PCOS...

Diet-induced metabolic syndrome model in rats

Background & Objective: Risk for heart disease, diabetes, and stroke increases with the number of the metabolic risk factors. In general, a person who has the metabolic syndrome is twice as likely to develop heart disease and five times as likely to develop diabetes as someone who does not have the metabolic syndrome. High-calorie-diet rodent models have contributed significantly to the analysi...

Rodent Models of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis

Research in nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), has been limited by the availability of suitable models for this disease. A number of rodent models have been described in which the relevant liver pathology develops in an appropriate metabolic context. These models are promising tools for researchers investigating one of the key issues of NASH...

Xanthine oxidoreductase in essential hypertension and metabolic syndrome : Experimental studies on rodent models

The Effect of Consumption of Unhealthy Snacks on Diet and the Risk of Metabolic Syndrome in Adults: Tehran Lipid and Glucose Study, Iran

Background & Aims: Unhealthy snacks contain high amounts of calories, simple sugars, fat, cholesterol, salt, additives, and conservatives. Increased consumption of these unhealthy snacks is one of the underlying factors for the prevalence of overweight, obesity, and metabolic disorders. In this study, we investigated the effects of unhealthy snacks on diet and the risk of metabolic syndrome aft...