Does Meniere’s Disease Really Increase Traveling Wave Velocity of the Basilar Membrane? Estimation with Frequency-Specific Electrocochleography*

نویسندگان

  • Deniz Sen
  • Bulent Satar
  • Sertac Yetiser
چکیده

Materials and Methods: This prospective study included three groups, 38 patients with Meniere’s disease (41 ears), 30 patients with cochlear hearing loss other than Meniere’s disease (40 ears) and 25 healthy subjects (40 ears). Tympanic membrane ECoG (click and tone-burst evoked) and caloric test were performed. Forty one ears with Meniere’s disease were categorized into definite (28 ears) and probable Meniere patients (13 ears) based on recommendation of the Committee on Hearing and Equilibrium of the American Academy of Otolaryngology-Head and Neck Surgery. Summation potential (SP) / action potential (AP) ratio and AP latency difference for 0.5 kHz and 2 kHz were measured in click and tone-burst evoked ECoG. In caloric test, unilateral weakness was sought. The patients were then further stratified based on abnormal SP/AP ratio and presence of UW. AP latency difference was compared among the groups and subgroups (based on SP/AP ratio and presence of UW).

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparison of Transtympanic and Extratympanic Electrocochleography

Electrocochleography (ECoG) has been an important tool in the diagnosis of Meniere’s disease or endolymphatic hydrops. There are two methods employed, transtympanic and extratympanic. Many have regarded the results of these methods as being equally reliable. The purpose of this study is to determine any differences in sensitivity between the two methods. In this study patients with known endoly...

متن کامل

HLA-Cw Allele Frequency in Definite Meniere’s Disease Compared to Probable Meniere’s Disease and Healthy Controls in an Iranian Sample

Introduction Several lines of evidence support the contribution of autoimmune mechanisms in the pathogenesis of Meniere’s disease. The aim of this study was determining the association between HLA-Cw Alleles in patients with definite Meniere’s disease and patients with probable Meniere’s disease and a control group.  Materials and Methods: HLA-Cw genotyping was performed in 23 patients with def...

متن کامل

Longitudinally propagating traveling waves of the mammalian tectorial membrane.

Sound-evoked vibrations transmitted into the mammalian cochlea produce traveling waves that provide the mechanical tuning necessary for spectral decomposition of sound. These traveling waves of motion that have been observed to propagate longitudinally along the basilar membrane (BM) ultimately stimulate the mechano-sensory receptors. The tectorial membrane (TM) plays a key role in this process...

متن کامل

Noninvasive in vivo imaging reveals differences between tectorial membrane and basilar membrane traveling waves in the mouse cochlea.

Sound is encoded within the auditory portion of the inner ear, the cochlea, after propagating down its length as a traveling wave. For over half a century, vibratory measurements to study cochlear traveling waves have been made using invasive approaches such as laser Doppler vibrometry. Although these studies have provided critical information regarding the nonlinear processes within the living...

متن کامل

Supporting evidence for reverse cochlear traveling waves.

As a result of the cochlea's nonlinear mechanics, stimulation by two tones results in the generation of distortion products (DPs) at frequencies flanking the primary tones. DPs are measurable in the ear canal as oto-acoustic emissions, and are used to noninvasively explore cochlear mechanics and diagnose hearing loss. Theories of DP emissions generally include both forward and reverse cochlear ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2009