Assemble: an interactive graphical tool to analyze and build RNA architectures at the 2D and 3D levels

نویسندگان

  • Fabrice Jossinet
  • Thomas E. Ludwig
  • Eric Westhof
چکیده

SUMMARY Assemble is an intuitive graphical interface to analyze, manipulate and build complex 3D RNA architectures. It provides several advanced and unique features within the framework of a semi-automated modeling process that can be performed by homology and ab initio with or without electron density maps. Those include the interactive editing of a secondary structure and a searchable, embedded library of annotated tertiary structures. Assemble helps users with performing recurrent and otherwise tedious tasks in structural RNA research. AVAILABILITY AND IMPLEMENTATION Assemble is released under an open-source license (MIT license) and is freely available at http://bioinformatics.org/assemble. It is implemented in the Java language and runs on MacOSX, Linux and Windows operating systems.

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عنوان ژورنال:

دوره 26  شماره 

صفحات  -

تاریخ انتشار 2010