Downregulation of Apelin in the Human Placental Chorionic Villi from Preeclamptic
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چکیده
Downregulation of Apelin in the Human Placental Chorionic Villi from Preeclamptic 1 Pregnancies 2 3 Liliya M. Yamaleyeva, Mark C. Chappell, K. Bridget Brosnihan, Lauren Anton, David L. 4 Caudell, Sara Shi, Carolynne McGee, Nancy Pirro, Patricia E. Gallagher, Robert N. Taylor, 5 David C. Merrill, Heather L. Mertz 6 7 Hypertension and Vascular Research Center, Department of Obstetrics and Gynecology, 8 Department of Pathology/Comparative Medicine, Wake Forest School of Medicine, Winston9 Salem, North Carolina, USA 10 11 Running Head: Apelin peptides in human placenta in preeclampsia 12 13 Corresponding author: 14 15 Liliya M. Yamaleyeva, MD, MS 16 Hypertension and Vascular Research Center 17 Wake Forest School of Medicine 18 Medical Center Blvd 19 Winston-Salem, NC 27157-1032 20 Phone: 336-716-2155 21 Fax: 336-716-2456 22 [email protected] 23 Articles in PresS. Am J Physiol Endocrinol Metab (September 22, 2015). doi:10.1152/ajpendo.00272.2015
منابع مشابه
Downregulation of apelin in the human placental chorionic villi from preeclamptic pregnancies.
The role of the endogenous apelin system in pregnancy is not well understood. Apelin's actions in pregnancy are further complicated by the expression of multiple forms of the peptide. Using radioimmunoassay (RIA) alone, we established the expression of apelin content in the chorionic villi of preeclamptic (PRE) and normal pregnant women (NORM) at 36-38 wk of gestation. Total apelin content was ...
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