Coeliac Disease With Rheumatoid Arthritis: An Unusual Association
نویسندگان
چکیده
Coeliac disease has a significant association with many autoimmune disorders. It shares many common genetic and immunological features with other autoimmune diseases. Gluten, a gut-derived antigen, is the driver of the autoimmunity seen in coeliac disease. The altered intestinal permeability found in coeliac patients, coupled with a genetic predisposition and altered immunological response, may result in a systemic immune response that is directed against sites other than the gut. Gut-derived antigens may have a role in the pathogenesis of other autoimmune disorders including rheumatoid arthritis. Here we report a case of adult coeliac disease associated with rheumatoid arthritis.
منابع مشابه
Association between obesity types and anthropometric indices with rheumatoid arthritis disease
Background: Obesity is one of the causes of onset and exacerbation of rheumatoid arthritis. However, limited studies have examined the association between body composition and severity of disease. The aim of this study was to evaluate the association between severity of rheumatoid arthritis with various types of obesity and the comparison of anthropometric indices between patients with rheumato...
متن کاملStudying the Association between STAT4 Gene Polymorphism and Susceptibility to Rheumatoid Arthritis Disease: An Updated Meta-Analysis
متن کامل
بررسی ارتباط HLA-DR4 و ساب تایپهای آن با ابتلا به آرتریت روماتوئید
Background: There are several evidences that genetic factors besides environmental triggers have important role in initiating the rheumatoid arthritis (RA). The aim of this study was to investigate the association of rheumatoid arthritis with different subtypes of HLA DR4 in Iranian patients. Methods: In an un-matched case control study, 110 rheumatoid arthritis patients (case) and 56 knee ost...
متن کاملCoeliac disease and rheumatoid arthritis.
Three cases are reported of adult coeliac disease associated with rheumatoid arthritis.
متن کاملCoeliac disease and autoimmunity.
Among fifty-seven patients with proven coeliac disease three also had thyrotoxicosis, two insulin dependant diabetes, three fibrosing alveolitis and one each had vitiligo, rheumatoid arthritis and cryptogenic cirrhosis. Autoantibodies were demonstrated in twelve of thirty-one patients tested, seven of these twelve had one of the above associated conditions. Antireticulin antibodies were found i...
متن کامل