Inappropriate use of commercial human chorionic gonadotropin assays.

Between-method variation in human chorionic gonadotropin test results.

BACKGROUND Results on sera and calibrators vary 1.4- to 2.3-fold among commercial human chorionic gonadotropin (hCG) assays. The relative contributions of calibrators, standards, hCG charge isoforms, and major structural variants to this variation have not been quantified. METHODS Purified hCG was separated by isoelectric focusing into four fractions with pI ranges of 3-4, 4-5, 5-6, and 6-7. ...

The potentiality of the functionalized nitrogen and thiol-doped graphene quantum dots (GQDs-N-S) to stabilize the antibodies in the designing of human chorionic gonadotropin immunosensor

In this study, for the first time, a simple immunosensor for ultrasensitive recognition of Human Chorionic Gonadotropin (hCG) in serum samples was fabricated by exploiting a simple approach. In this method, a low-cost and sensitive immunosensor was fabricated based on QDs-N-S/Au nanoparticles (NPs) modified Screen-Printed Carbon Electrode (SPCE). It seems that, QDs-N-S/Au NPs/ antibody as a bio...

Effect of Adding Human Chorionic Gonadotropin to The Endometrial Preparation Protocol in Frozen Embryo Transfer Cycles

P-165: Comparison of Urinary and Recombinant Human Chorionic Gonadotropin during Ovulation Induction in Intrauterine Insemination Cycles

Background: Urinary human chorionic gonadotropin is the most widely used medicine for ovulation in ovarian stimulation cycles. Recently however, recombinant HCG has also become commercially available. This study presents compare the use of recombinant hCG with urinary hCG during controlled ovarian hyperstimulation and intra uterine insemination (COH-IUI ) cycles Materials and Methods: This is s...

Utility of commonly used commercial human chorionic gonadotropin immunoassays in the diagnosis and management of trophoblastic diseases.

BACKGROUND Patients with trophoblastic diseases produce ordinary and irregular forms of human chorionic gonadotropin (hCG; e.g., nicked hCG, hCG missing the beta-subunit C-terminal segment, hyperglycosylated hCG, and free beta subunit) that are recognized to differing extents by automated immunometric hCG (or hCG beta) assays. This has led to low or false-negative results and misdiagnosis of pe...