Activation of telomerase in glioma cells by human cytomegalovirus: another piece of the puzzle.
نویسندگان
چکیده
Comment on: J Natl Cancer Inst. 2009 Apr 1;101(7):488-97. Activation of telomerase in glioma cells by human cytomegalovirus: another piece of the puzzle. Cinatl J Jr, Nevels M, Paulus C, Michaelis M. Publication Types: Comment Editorial Review PMID: 19318630 [PubMed indexed for MEDLINE] A service of the U.S. National Library of Medicine and the National Institues of Health Page 1 of 1 PubMed Results Print Preview
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Human cytomegalovirus infection in tumor specimens of Iranian patients with glioma
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BACKGROUND The mechanism by which human cytomegalovirus (HCMV) stimulates oncogenesis is unclear. Because cellular immortalization and transformation require telomerase activation by expression of the telomerase reverse transcriptase (hTERT) gene, we examined the role of HCMV in telomerase activation. METHODS Normal human diploid fibroblasts (HDFs) and human malignant glioma (MG) cell lines w...
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ورودعنوان ژورنال:
- Journal of the National Cancer Institute
دوره 101 7 شماره
صفحات -
تاریخ انتشار 2009