Cellthe Peripheral Activated / Memory CD 4 T Regulatory CD 4 T Cells Control
نویسندگان
چکیده
منابع مشابه
بررسی تعداد سلولهای T تنظیمی در بیماران مبتلا به بیماری کرون
Background and purpose: Crohn disease (CD) is an autoimmune disorder in which a failure of tolerance to the intestinal antigens plays a pivotal role in the pathogenesis of this disease. Treg cells control immune responses to self and foreign antigens and have an important role in maintaining self-tolerance. In this study we evaluated the frequency of Tregs in the peripheral blood of patients wi...
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Proportional changes of lymphocyte subsets in the peripheral blood were monitored by two-color flow-cytometry in seven leukemia patients who had received allogenic bone marrow transplantation (BMT). Lymphocyte counts, and proportions of T and B-cells returned to normal ranges between the 2nd and 12th months after BMT. Activated T-cells prominently increased after BMT, and the values gradually r...
متن کاملCytokine profiles in peripheral blood of children and adults with Crohn disease.
BACKGROUND Increasing evidence suggests that cytokine dysregulation in T-helper 1 and T-helper 2 (TH1/TH2) subsets contributes to the pathogenesis of Crohn disease (CD). The present pilot study examines the hypothesis that cytokine profiles differ between pediatric and adult patients with CD. METHODS Production of TH1 cytokines interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) ...
متن کاملAfter Moving of Regulatory T-Cell Therapy to the Clinic: Will We Need a New Tregs Source?
Submit Manuscript | http://medcraveonline.com Abbreviations: AMP: Adenosine Monophosphate; ATP: Adenosine Triphosphate; cAMP: Cyclic Adenosine Monophosphate; CD: Cluster of Differentiation; CTLA-4: Cytotoxic T-LymphocyteAssociated Protein 4; IDO: Indoleamine 2,3-dioxygenase; IFN: Interferon; IL: Interleukin; LAG3: Lymphocyte-Activation Gene 3; TCR: T Cell Receptor; TGF-β: Transforming Growth Fa...
متن کاملT Lymphocytes in AIDS Patients With Tuberculosis
CD 4 + and CD 8 + T lymphocyte counts, naive and memory/effector CD 4 + T subpopulations, and the expression of CD 38 on CD 8 + T lymphocytes were evaluated in four groups: AIDS patients with tuberculosis (HIV/TB, n=14), HIV-1 infected patients (HIV, n=10), HIV-1 negative patients with tuberculosis (TB, n=20) and healthy controls (CTL, n=17). TB and HIV had fewer CD 4 + T cells than CTL, with t...
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