Resting-state fMRI contributes to differentiate patients with dementia with Lewy bodies from those with Alzheimer's disease
نویسندگان
چکیده
B. Basile, M. Cercignani, L. Serra, R. Perri, C. Marra, L. Fadda, C. Caltagirone, and M. Bozzali Neuroimaging Laboratory, Santa Lucia Foundation, Rome, Italy, Italy, Clinical and Behavioural Neurology Laboratory, Santa Lucia Foundation, Rome, Italy, Italy, Department of Neurosciences, Catholic University of Rome, Roma, Italy, Italy, Department of Neurosciences, University of Torvergata, Rome, Italy, Italy
منابع مشابه
Resting state fMRI brain network connectivity in dementia with Lewy bodies and Alzheimer’s disease
Peraza LR, Kaiser M, Firbank M, Graziadio S, O'Brien J, Taylor J-P. Resting state fMRI brain network connectivity in dementia with Lewy bodies and Alzheimer's disease. In: 20th Annual Meeting of the Organization for Human Brain Mapping (OHBM 2014). 2014, Hamburg, Germany: Organization for Human Brain Mapping. Copyright: © The Authors Poster presented at the 20 Annual Meeting of the Organization...
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BACKGROUND Resting-state functional magnetic resonance imaging (fMRI) can be used to measure correlations in spontaneous low-frequency fluctuations in the blood oxygen level-dependent (BOLD) signal which represent functional connectivity between key brain areas. AIMS To investigate functional connectivity with regions hypothesised to be differentially affected in dementia with Lewy bodies (DL...
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Using resting-state functional magnetic resonance imaging, spontaneous low-frequency fluctuations in the blood oxygenation level-dependent signal were measured to investigate connectivity between key brain regions hypothesized to be differentially affected in dementia with Lewy bodies compared with Alzheimer's disease and healthy controls. These included connections of the hippocampus, because ...
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The clinical phenotype of dementia with Lewy bodies (DLB) is different from Alzheimer's disease (AD), suggesting a divergence between these diseases in terms of brain network organization. To fully understand this, we studied functional networks from resting-state functional magnetic resonance imaging in cognitively matched DLB and AD patients. The DLB group demonstrated a generalized lower syn...
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