Evaluation of a MRL Diagnostic IgM Capture ELISA Kit for Dengue Diagnosis

Primary, secondary and even tertiary dengue infections can be detected taking into account the existence of four serotypes. During a primary infection, individuals develop IgM antibodies 5–6 days after the onset of illness lasting 30 to 90 days. IgG levels rise after IgM and are detectable for life[7]. During a secondary infection IgM levels are lower and in some cases absent. In contrast, IgG levels rise rapidly to higher levels than observed in primary or past dengue infection. Consequently, it is useful to combine the detection of specific IgM and IgG for serological diagnosis of dengue virus infection[8].