Methylmercury blood guidance values for Canada.

نویسندگان

  • Melissa Legrand
  • Mark Feeley
  • Constantine Tikhonov
  • Deborah Schoen
  • Angela Li-Muller
چکیده

Exposure to methylmercury (MeHg) from fish and marine mammal consumption continues to present a public health concern. To date, developmental neurotoxicity is the most sensitive health outcome, forming the basis for health-risk assessments and the derivation of biomonitoring guidance values. This article summarizes existing Health Canada MeHg blood guidance values for general population and expands them to include a harmonized provisional interim blood guidance value of 8 microg/L based on the existing provisional Tolerable Daily Intake for children, pregnant women and women of childbearing age. Associated public health actions, according to age, sex, and level of exposure are recommended.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Exposure of Arctic populations to methylmercury from consumption of marine food: an updated risk-benefit assessment.

Recent and powerful epidemiological studies have been used as a basis for revising international and domestic guidelines for human exposure to mercury. Long-range transport of mercury into the Arctic makes some Arctic peoples consuming traditional marine foods, especially newborns, children and pregnant women, very vulnerable to harmful exposures. The WHO, the USEPA and Health Canada have all r...

متن کامل

Hair Mercury Levels in Six Iranian Sub-populations for Estimation of Methylmercury Exposure: A Mini-review

Background: Mercury is widespread and persistent in the environment. One organic form of mercury, Methylmercury (MeHg), can accumulate in the food chain in aquatic ecosystems and lead to high concentrations of MeHg in fish, which, when consumed by humans, can result in an increased risk of adverse effects. Currently, the Joint FAO/WHO Expert Committee on Food Additives (JECFA) has established...

متن کامل

Estimation of the Biological Half-Life of Methylmercury Using a Population Toxicokinetic Model

Methylmercury is well known for causing adverse health effects in the brain and nervous system. Estimating the elimination constant derived from the biological half-life of methylmercury in the blood or hair is an important part of calculating guidelines for methylmercury intake. Thus, this study was conducted to estimate the biological half-life of methylmercury in Korean adults. We used a one...

متن کامل

Reducing Periconceptional Methylmercury Exposure: Cost-Utility Analysis for a Proposed Screening Program for Women Planning a Pregnancy in Ontario, Canada.

BACKGROUND The assessment of neurodevelopmental effects in children associated with prenatal methylmercury exposure, from contaminated fish and seafood in the maternal diet, has recently been strengthened by adjustment for the negative confounding resulting from co-exposure to beneficial polyunsaturated fatty acids (PUFAs). OBJECTIVES We aimed to determine the cost-effectiveness of a periconc...

متن کامل

Associations of methylmercury and inorganic mercury between human cord blood and maternal blood: a meta-analysis and its application.

Considering the different ability of placental transfer, an assessment of the cord:maternal blood ratio for both methylmercury (MeHg) and inorganic mercury (IHg) is needed especially for interpreting the low-level prenatal exposure. In this study, we conducted a Monte Carlo-based meta-analysis to comprehensively estimate that ratio for MeHg (RMeHg) and IHg (RIHg). The obtained values followed l...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Canadian journal of public health = Revue canadienne de sante publique

دوره 101 1  شماره 

صفحات  -

تاریخ انتشار 2010