Pancreatic panniculitis preceding acute pancreatitis and subsequent detection of an intraductal papillary mucinous neoplasm: A case report

CT: computed tomography EUS: endoscopic ultrasound scan IPMN: intraductal papillary mucinous neoplasm MRCP: magnetic resonance cholangiopancreatography MPD: main pancreatic duct INTRODUCTION Pancreatic panniculitis is a rare skin manifestation of pancreatic disease. It is believed to result from seepage of pancreatic enzymes into the systemic circulation, which leads to skin and occasionally joint manifestations. It is reported to occur in up to 3% of patients with pancreatic disease. Pancreatic panniculitis can develop before, concomitantly with, or after the diagnosis of clinically detectable pancreatic conditions. The condition is most frequently associated with acute pancreatitis, chronic pancreatitis, and pancreatic carcinoma. The most common carcinoma is acinar cell type. Here we report an unusual association of pancreatic panniculitis preceding a single episode of acute pancreatitis and subsequent development of an intraductal papillary mucinous neoplasm (IPMN).