Secomycalolide A: A New Proteasome Inhibitor Isolated from a Marine Sponge of the Genus Mycale

نویسندگان

  • Sachiko Tsukamoto
  • Keiichirou Koimaru
  • Tomihisa Ohta
چکیده

A new oxazole-containing proteasome inhibitor, secomycalolide A, together with known mycalolide A and 30-hydroxymycalolide A, was isolated from a marine sponge of the genus Mycale. They showed proteasome inhibitory activities with IC50 values of 11-45 μg/mL.

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عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2005