Sit and stay a while: how BfiSR controls irreversible attachment in Pseudomonas aeruginosa biofilms.
نویسنده
چکیده
منابع مشابه
A Novel Signaling Network Essential for Regulating Pseudomonas aeruginosa Biofilm Development
The important human pathogen Pseudomonas aeruginosa has been linked to numerous biofilm-related chronic infections. Here, we demonstrate that biofilm formation following the transition to the surface attached lifestyle is regulated by three previously undescribed two-component systems: BfiSR (PA4196-4197) harboring an RpoD-like domain, an OmpR-like BfmSR (PA4101-4102), and MifSR (PA5511-5512) b...
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The interaction of Pseudomonas aeruginosa with surfaces has been described as a two-stage process requiring distinct signaling events and the reciprocal modulation of small RNAs (sRNAs). However, little is known regarding the relationship between sRNA-modulating pathways active under planktonic or surface-associated growth conditions. Here, we demonstrate that SagS (PA2824), the cognate sensor ...
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This chapter aims to describe the early stages of biofilm formation, particularly on abiotic surfaces, by focusing on Pseudomonas aeruginosa. Specifically, we will dissect the early steps in the establishment of a multicellular community: (i) translocation to the surface from a free-swimming planktonic lifestyle, (ii) initial or reversible attachment, and finally (iii) irreversible attachment. ...
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Pseudomonas aeruginosa responds to environmental changes and regulates its life cycle from planktonic to biofilm modes of growth. The control of cell attachment to surfaces is one of the critical processes that determine this transition. Environmental signals are typically relayed to the cytoplasm by second messenger systems. We here demonstrated that the second messenger, cAMP, regulated the a...
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 192 20 شماره
صفحات -
تاریخ انتشار 2010