Extreme Hypersensitiveness to Cow's Milk Protein in an Infant.

Park' reports the case of a breast-fed infant which, at the age of six weeks was given a little cow's milk and which, after three or four hours, vomited, became collapsed, and later had diarrhcea. The child was desensitized by the mouth with gradually increasing doses beginning with 0.0001 c.cm. until large quantities of milk could be tolerated. Weill2 had a similar case which was cured by subcutaneous injection of doses of from 5 to 10 c.cm. of autoclaved cow's milk; as Coke3 points out, the autoclaving of the milk would appear to place the treatment in the category of non-specific protein therapy. Coke4 describes a case in a breast-fed infant, which was, during a short illness of the mother, fed on cow's milk (which was well borne) for 48 hours. On weaning, it was found that the child could not take cow's milk, having been sensitized bv the previous isolated ' doses.'