Drift ratchet
نویسندگان
چکیده
We consider a silicon wafer, pierced by millions of identical pores with periodically varying diameters but without spatial inversion symmetry (ratchet profile). When a liquid is periodically pumped back and forth through the pores, our theory predicts a net transport of suspended micrometer-sized particles (drift ratchet). The direction of this particle current depends very sensitively on the size of the particles. For typical parameter values of the experiment, two different types of particles at an initially homogeneous 1:1 mixture are spatially separated with a purity beyond 1:1000 on a time scale of a few hours in comparably large quantities. This result is due to the highly parallel architecture of the device. The experimental realization of the setup, presently under construction, thus appears to be a promising new particle separation device, possibly superior to existing methods for particles sizes on the micrometer scale.
منابع مشابه
Collective ratchet effects and reversals for active matter particles on quasi-one-dimensional asymmetric substrates.
Using computer simulations, we study a two-dimensional system of sterically interacting self-mobile run-and-tumble disk-shaped particles with an underlying periodic quasi-one-dimensional asymmetric substrate, and show that a rich variety of collective active ratchet behaviors arise as a function of particle density, activity, substrate period, and the maximum force exerted by the substrate. The...
متن کاملAsymptotic properties of certain diffusion ratchets with locally negative drift
We consider two reflecting diffusion processes (Xt)t≥0 with a moving reflection boundary given by a non-decreasing pure jump Markov process (Rt)t≥0. Between the jumps of the reflection boundary the diffusion part behaves as a reflecting Brownian motion with negative drift or as a reflecting Ornstein-Uhlenbeck process. In both cases at rate γ(Xt − Rt) for some γ ≥ 0 the reflection boundary jumps...
متن کاملBiological evolution through mutation, selection, and drift: An introductory review
5 Modelling mutational degeneration 23 5.1 Error thresholds . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 5.1.1 The prototype model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 5.1.2 Methods of analysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 5.1.3 Characterization of error thresholds . . . . . . . . . . . . . . . . . . . . ....
متن کاملMutational Meltdown in Primary Endosymbionts: Selection Limits Muller's Ratchet
BACKGROUND Primary bacterial endosymbionts of insects (p-endosymbionts) are thought to be undergoing the process of Muller's ratchet where they accrue slightly deleterious mutations due to genetic drift in small populations with negligible recombination rates. If this process were to go unchecked over time, theory predicts mutational meltdown and eventual extinction. Although genome degradation...
متن کاملMuller's ratchet decreases fitness of a DNA-based microbe.
Muller proposed that an asexual organism will inevitably accumulate deleterious mutations, resulting in an increase of the mutational load and an inexorable, ratchet-like, loss of the least mutated class [Muller, H.J. (1964) Mutat. Res. 1, 2-9]. The operation of Muller's ratchet on real populations has been experimentally demonstrated only in RNA viruses. However, these cases are exceptional in...
متن کاملStokes' Drift: a Rocking Ratchet
We derive the explicit analytic expression for the Stokes' drift in one dimension in the presence of a dichotomic Markov forcing. For small amplitudes of the forcing, the drift is enhanced, but the enhancement is reduced with increasing frequency of the forcing. On the other hand, a reduction of the drift or even a flux reversal can be induced at larger amplitudes, while the flux is now found t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics
دوره 61 1 شماره
صفحات -
تاریخ انتشار 2000