Durability of treatment of intracranial aneurysms with hydrocoils is not different from standard platinum coils.
نویسندگان
چکیده
Durability of Treatment of Intracranial Aneurysms With Hydrocoils Is Not Different From Standard Platinum Coils To the Editor: With interest we read the article by Gaba et al1 about the use of Hydrocoils for 50 intracranial aneurysms. The results were compared with a matched historical control group of 57 aneurysms treated with standard coils. We have some concerns about the methodology. First of all, aneurysm volume assessment assuming the aneurysm to be an ellipsoid is notoriously inaccurate2,3 and may account for the reported volumetric percentage occlusion of over 100% in more than half of the aneurysms. In addition, no standard angiographic follow-up interval to detect reopening was available and follow-up interval for aneurysms treated with standard coils was significantly longer. More aneurysms treated with standard coils were coiled with balloon remodelling (21 versus 7) indicating that more of these aneurysms had wide necks which may have influenced reopening rate. A dazzling amount of confusing data are presented and interpreted toward better results of Hydrocoil. In fact, the bottom line of durability of treatment is the retreatment rate at follow-up, which is influenced by many other factors besides aneurysm volume and volumetric occlusion such as follow-up interval, proportion of partially thrombosed aneurysms and proportion of wide-necked aneurysms. A difference in retreatment of 4 of 41 aneurysms treated with Hydrocoil versus 7 of 41 aneurysms treated with standard coils is not significant, and both numbers are in the expected range of platinum coils.4,5 If these nonsignificant differences make the authors conclude that Hydrocoils are superior, a similar way of interpretation of results would conclude a higher complication rate (4% versus 0%) in aneurysms treated with Hydrocoils. One may wonder why such an effort is made to make the reader believe that results of Hydrocoils are better. Possibly the answer lies in the acknowledgments and colophon.
منابع مشابه
Embolization of intracranial aneurysms with hydrogel-coated coils versus inert platinum coils: effects on packing density, coil length and quantity, procedure performance, cost, length of hospital stay, and durability of therapy.
BACKGROUND AND PURPOSE The durability of aneurysm coil embolization is thought to depend on packing density. The expansile property of hydrogel coating on coils increases volumetric packing per coil length. We describe our experience using hydrogel-coated coils (HydroCoils) compared with inert platinum coils in intracranial aneurysm embolization. METHODS Fifty aneurysms embolized primarily us...
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BACKGROUND AND PURPOSE A report directly comparing platinum coils, Matrix coils, and HydroCoils in a single animal model does not currently exist. We evaluated and compared the performance of these three products in the embolization of experimental aneurysms. METHODS Thirty-three elastase-induced saccular aneurysms were created in rabbits. Aneurysms were embolized with Matrix coils (n = 15), ...
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BACKGROUND AND PURPOSE The HydroCoil Endovascular Aneurysm Occlusion and Packing Study (HELPS) was a randomized, controlled trial comparing HydroCoils with bare-platinum coils. The purpose of this study was to perform a subgroup analysis of angiographic and clinical outcomes of medium-sized aneurysms in the HELPS trial. MATERIALS AND METHODS Patients with medium-sized aneurysms (5-9.9 mm) wer...
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ورودعنوان ژورنال:
- Stroke
دوره 37 12 شماره
صفحات -
تاریخ انتشار 2006