A Fast Lesion Registration to Assist Coronary Heart Disease Diagnosis in CTA Images

This work introduces a 3D+t coronary registration strategy to minimize the navigation among cardiac phases during the process of ischaemic heart disease diagnosis. We propose to register image subvolumes containing suspected arterial lesions at two cardiac phases, instead of performing a registration of the complete cardiac volume through the whole cardiac cycle. The method rst automatically de nes the extent of the sub-volumes to be aligned, then the registration is performed in two steps: a coarse rigid alignment and a deformable registration. Our method provides comparable results and is computationally less expensive than previous approaches that make use of larger spatial and temporal information.