Sequencing of Culex quinquefasciatus establishes a platform for mosquito comparative genomics.

نویسندگان

  • Peter Arensburger
  • Karine Megy
  • Robert M Waterhouse
  • Jenica Abrudan
  • Paolo Amedeo
  • Beatriz Antelo
  • Lyric Bartholomay
  • Shelby Bidwell
  • Elisabet Caler
  • Francisco Camara
  • Corey L Campbell
  • Kathryn S Campbell
  • Claudio Casola
  • Marta T Castro
  • Ishwar Chandramouliswaran
  • Sinéad B Chapman
  • Scott Christley
  • Javier Costas
  • Eric Eisenstadt
  • Cedric Feschotte
  • Claire Fraser-Liggett
  • Roderic Guigo
  • Brian Haas
  • Martin Hammond
  • Bill S Hansson
  • Janet Hemingway
  • Sharon R Hill
  • Clint Howarth
  • Rickard Ignell
  • Ryan C Kennedy
  • Chinnappa D Kodira
  • Neil F Lobo
  • Chunhong Mao
  • George Mayhew
  • Kristin Michel
  • Akio Mori
  • Nannan Liu
  • Horacio Naveira
  • Vishvanath Nene
  • Nam Nguyen
  • Matthew D Pearson
  • Ellen J Pritham
  • Daniela Puiu
  • Yumin Qi
  • Hilary Ranson
  • Jose M C Ribeiro
  • Hugh M Roberston
  • David W Severson
  • Martin Shumway
  • Mario Stanke
  • Robert L Strausberg
  • Cheng Sun
  • Granger Sutton
  • Zhijian Jake Tu
  • Jose Manuel C Tubio
  • Maria F Unger
  • Dana L Vanlandingham
  • Albert J Vilella
  • Owen White
  • Jared R White
  • Charles S Wondji
  • Jennifer Wortman
  • Evgeny M Zdobnov
  • Bruce Birren
  • Bruce M Christensen
  • Frank H Collins
  • Anthony Cornel
  • George Dimopoulos
  • Linda I Hannick
  • Stephen Higgs
  • Gregory C Lanzaro
  • Daniel Lawson
  • Norman H Lee
  • Marc A T Muskavitch
  • Alexander S Raikhel
  • Peter W Atkinson
چکیده

Culex quinquefasciatus (the southern house mosquito) is an important mosquito vector of viruses such as West Nile virus and St. Louis encephalitis virus, as well as of nematodes that cause lymphatic filariasis. C. quinquefasciatus is one species within the Culex pipiens species complex and can be found throughout tropical and temperate climates of the world. The ability of C. quinquefasciatus to take blood meals from birds, livestock, and humans contributes to its ability to vector pathogens between species. Here, we describe the genomic sequence of C. quinquefasciatus: Its repertoire of 18,883 protein-coding genes is 22% larger than that of Aedes aegypti and 52% larger than that of Anopheles gambiae with multiple gene-family expansions, including olfactory and gustatory receptors, salivary gland genes, and genes associated with xenobiotic detoxification.

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عنوان ژورنال:
  • Science

دوره 330 6000  شماره 

صفحات  -

تاریخ انتشار 2010