[Rectal barostat in irritable bowel syndrome].

نویسندگان

  • Claudia Defilippi G
  • Rodrigo Quera P
  • Ana María Madrid S
  • Carlos Defilippi C
  • Jorge Valenzuela E
چکیده

BACKGROUND Many patients with irritable bowel syndrome (IBS) have lowered sensory thresholds to rectal distention when compared to control subjects, a phenomenon called visceral hypersensitivity. AIM To investigate the usefulness of a rectal barostat as a diagnostic tool in IBS and if there are differences in visceral hypersensitivity in different groups of IBS patients. PATIENTS AND METHODS Ten healthy subjects and 19 IBS patients, defined using Rome II criteria (12 with constipation, three with diarrhea and four alternating between diarrhea and constipation), were studied. Sequential isobaric rectal distentions, from 2 mmHg up to a maximal pressure of 52 mmHg or when the patients reported pain, were carried out. Visceral hypersensitivity was defined as a pain threshold under 38 mmHg. RESULTS Only 26% of IBS patients had visceral hypersensitivity (16% and 43% of patients with IBS and constipation and IBS and diarrhea or alternating symptoms, respectively, p =NS). Pain threshold in controls, patients with IBS and constipation and patients with IBS and diarrhea or alternating symptoms was 43.8+/-6.6, 45.3+/-9.2 and 40.8+/-9.2 mmHg, respectively (p =NS). CONCLUSIONS Our results do not support the usefulness of the electronic rectal barostat as a diagnostic method to diagnose IBS.

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عنوان ژورنال:
  • Revista medica de Chile

دوره 134 12  شماره 

صفحات  -

تاریخ انتشار 2006