Q&A: Epistasis

Fine, so what does a population geneticist mean by epistasis? RA Fisher used ‘epistacy’ and later ‘epistasis’ to describe genetic interactions more generally [2]. We think that population geneticists hijacked this term over a decade after its coinage just to confuse the classical geneticists. OK, what does a medical doctor mean by epistasis? A thin film on the surface of a urine specimen. Enough said on that topic.