The diagnostic value of faecal trypsin estimation in chronic pancreatic disease.
نویسندگان
چکیده
Faecal trypsin levels have been estimated by a photometric azo-casein method in 242 children and 45 adults. Analysis of the results shows that this is not a specific test of pancreatic dysfunction but that it appears to be a useful screening test for the selection of patients who may have severe pancreatic disease and on whom further specific investigations should be performed.
منابع مشابه
Faecal elastase 1: a novel, highly sensitive, and specific tubeless pancreatic function test.
BACKGROUND Indirect pancreatic function tests available today are unreliable for clinical practice in early chronic pancreatitis due to their low sensitivity in mild and moderate exocrine pancreatic insufficiency. AIM To evaluate the sensitivity, specificity, and practicability of faecal elastase 1 determination in patients with mild, moderate, and severe exocrine pancreatic insufficiency cat...
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EDITORIAL COMMENT The concentration of trypsin in duodenal contents following a Lundh test meal containing 6% of fat, 5% protein, and 15% carbohydrate, has been used as an index of exocrine pancreatic function. Low concentrations of trypsin are found in pancreatic disease, such as chronic pancreatitis and cancer of the pancreas. The test is particularly useful in the diagnosis of pancreatic ste...
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BACKGROUND/AIM The suggestion that estimation of faecal elastase 1 is a valuable new tubeless pancreatic function test was evaluated by comparing it with faecal chymotrypsin estimation in patients categorised according to grades of exocrine pancreatic insufficiency (EPI) based on the gold standard tests, the secretin-pancreozymin test (SPT) and faecal fat analysis. METHODS In 64 patients in w...
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ورودعنوان ژورنال:
- Journal of clinical pathology
دوره 15 1 شماره
صفحات -
تاریخ انتشار 1962