Peptic ulceration and phenylketonuria: a possible link?

The association between aneurysm of the abdominal aorta and peptic ulceration.

In a survey of 7,044 necropsies there were 99 cases of aneurysm of the abdominal aorta and 523 cases of peptic ulceration. The incidence of peptic ulceration in the general necropsy population was 7.2% whilst in cases with aneurysm it was 22.6%. There was a significant increase in duodenal ulceration in males with abdominal aortic aneurysms. The possible causes for this increased incidence are ...

Peptic ulceration in Crohn's disease (reional enteritis).

The incidence of peptic ulceration in a personal series of 300 patients with Crohn's disease was 8%. Resection of 60 or more centimetres of the small intestine was associated with significantly increased acid output, both basally and following pentagastrin stimulation. Only five (4%) of the 124 patients who received steroid steroid therapy developed peptic ulceration. It is suggested that resec...

Effect of diet on faecal and urine urobilinogen excretion and its possible relationship to the pathogenesis of peptic ulceration.

A comparison of home and hospital treatment of patients with peptic ulceration on a liberal diet.

In a previous paper3 I concluded that treatment in hospital of patients with peptic ulceration on a liberal diet gave results as good as those obtained in hospital by strict dieting, strict dieting plus robaden or a liberal diet plus robaden. Doll2 also found that patients with gastric ulcers treated in hospital did as well on an almost normal diet as those given a strict ulcer diet. He found t...

Cigarette smoking, chronic peptic ulceration, and pepsin 1 secretion.

The relationship between the secretion of pepsin 1 (the most electronegative of the pepsins), and the smoking habits of 219 patients has been investigated. Significantly more cigarette smokers with peptic ulceration (72.5%) secreted pepsin 1 in greater than trace amounts after pentagastrin or histamine than did non-smokers with ulceration (51.2%). Differences of a similar order were found for m...