International Journal of Pharma and Bio Sciences V1(1)2010 EXPLORATION IN SYNTHESIS AND FUNGICIDAL ACTIVITIES OF SOME NOVEL O-ETHYL O-HETEROARYL 2-CHLOROETHYL PHOSPHONATES
نویسنده
چکیده
Novel O-ethyl O-heteroaryl 2-chloroethyl phosphonates have been prepared by condensing 2chloroethyl phosphonyl dichloride by the sequential addition of ethanol and –OH and –SH carrying heteroaryls. Attempts of the above reaction with –NH carrying heteroaryl (benzimidazole) furnished a different product than the expected one by different reaction path.
منابع مشابه
Simple Synthesis and Biological Evaluation of Some Benzimidazoles Using Sodium Hexafluroaluminate, Na3AlF6, as an Efficient Catalyst
Considerable attention has been focused on the synthesis of benzimidazoles due to having a broad spectrum of biological activities such as anti-parasitic, fungicidal, anti-thelemintic and anti-inflammatory activities. As a part of our research work in this area, a series of benzimidasole derivatives (3a-n) were synthesized in good to high yields by reaction of o-phenylenediamine and different a...
متن کاملSimple Synthesis and Biological Evaluation of Some Benzimidazoles Using Sodium Hexafluroaluminate, Na3AlF6, as an Efficient Catalyst
Considerable attention has been focused on the synthesis of benzimidazoles due to having a broad spectrum of biological activities such as anti-parasitic, fungicidal, anti-thelemintic and anti-inflammatory activities. As a part of our research work in this area, a series of benzimidasole derivatives (3a-n) were synthesized in good to high yields by reaction of o-phenylenediamine and different a...
متن کاملSynthesis of Some New Quinazolinone Derivatives and Evaluation of Their Antimicrobial Activities
Wide range of quinazolinone biological properties including: antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. Anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. Deoxyvasicinone which wa...
متن کاملSynthesis of Some New Quinazolinone Derivatives and Evaluation of Their Antimicrobial Activities
Wide range of quinazolinone biological properties including: antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. Anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. Deoxyvasicinone which wa...
متن کاملMicrowave Assistant Synthesis, Antifungal Activity and DFT Theoretical Study of Some Novel 1,2,4-Triazole Derivatives Containing Pyridine Moiety
In order to investigate the biological activity of novel 1,2,4-triazole compounds, seventeen novel 1,2,4-triazole derivatives containing pyridine moiety were synthesized under microwave assistant condition by multi-step reactions. The structures were characterized by 1H NMR, MS and elemental analyses. The target compounds were evaluated for their fungicidal activities against Stemphylium lycope...
متن کامل