PReS-FINAL-2225: Oxidative stress in children with episodic fever of unknown origin
نویسندگان
چکیده
Introduction Fever of unknown origin (FOU) i.e.: (1) a temperature greater than 38.3°C on several occasions, (2) more than 3 weeks’ duration of illness, and (3) failure to reach a diagnosis despite 1 week of inpatient investigation are commonly seen in pediatric practice. The conditions could be caused by mutations of genes coding inflammasome sequences. In these instances activated neutrophils and monocytes intensively generate reactive oxidative species.
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