FcRn is mother's milk to allergen tolerance.

نویسنده

  • Bart N Lambrecht
چکیده

In this issue Ohsaki et al. (https://doi.org/10.1084/jem.20171163) explain how breastfeeding can prevent the onset of food allergies in offspring by instructing T reg formation via neonatal Fc receptor (FcRn)-mediated transfer and uptake of allergen-containing IgG immune complexes (Ig-ICs) by gut dendritic cells (DCs).

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منابع مشابه

FcRn is mother’s milk to allergen tolerance

Allergy is characterized by the presence of serum IgE antibodies to common and harmless environmental and food allergens and can lead to allergic diseases like asthma, rhinitis, food allergy, and anaphylaxis. As allergy is highly prevalent is Western societies, and there seems to be no halt to the epidemic of food allergy, there is an urgent need for preventive strategies (Lambrecht and Hammad,...

متن کامل

FcRn is mother’s milk to allergen tolerance

Allergy is characterized by the presence of serum IgE antibodies to common and harmless environmental and food allergens and can lead to allergic diseases like asthma, rhinitis, food allergy, and anaphylaxis. As allergy is highly prevalent is Western societies, and there seems to be no halt to the epidemic of food allergy, there is an urgent need for preventive strategies (Lambrecht and Hammad,...

متن کامل

FcRn is mother’s milk to allergen tolerance

Allergy is characterized by the presence of serum IgE antibodies to common and harmless environmental and food allergens and can lead to allergic diseases like asthma, rhinitis, food allergy, and anaphylaxis. As allergy is highly prevalent is Western societies, and there seems to be no halt to the epidemic of food allergy, there is an urgent need for preventive strategies (Lambrecht and Hammad,...

متن کامل

FcRn is mother’s milk to allergen tolerance

Allergy is characterized by the presence of serum IgE antibodies to common and harmless environmental and food allergens and can lead to allergic diseases like asthma, rhinitis, food allergy, and anaphylaxis. As allergy is highly prevalent is Western societies, and there seems to be no halt to the epidemic of food allergy, there is an urgent need for preventive strategies (Lambrecht and Hammad,...

متن کامل

FcRn is mother’s milk to allergen tolerance

Allergy is characterized by the presence of serum IgE antibodies to common and harmless environmental and food allergens and can lead to allergic diseases like asthma, rhinitis, food allergy, and anaphylaxis. As allergy is highly prevalent is Western societies, and there seems to be no halt to the epidemic of food allergy, there is an urgent need for preventive strategies (Lambrecht and Hammad,...

متن کامل

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عنوان ژورنال:
  • The Journal of experimental medicine

دوره 215 1  شماره 

صفحات  -

تاریخ انتشار 2018