Colicins and other bacteriocins with established modes of action.

INTRODUCTION ........................................................................................................ 125 COLICIN E2 AND E3 AND CLOACIN DF!3 ........................................................ !26 Mode of Action .......................................................................................................... 126 General Structure ...................................................................................................... 127 Immunity System ...................................................................................................... 127 Functional and Structural Domains ........................................................................ 128 COLICINS A, E! la, Ib, and K .................................................................................. 129 Mode of Action .......................................................................................................... 129 Structural Features .................................................................................................... 131 Immunity System ...................................................................................................... 132 COLICIN L .................................................................................................................... 1 33 COLICIN IV,[ ................................................................. ................................................. 133 TO THE TARGET ........................................................................................................ 134 Role of Receptors ....................................................................................... ............... 134 Possible Role 0/ Proteases ........................................................................................ 134 Colicin Uptake .......................................................................................................... 1 35 PESTICIN A 1 122 ....... . . ................ ............ . . . ............................ . . . ........... ........................ 136 STAPHYLOCOCCIN 1580 .......................................................................................... 137 BUTYRICIN 7423 ... . . . .......... . . ........ . . . . . . ........... .................. ........... . . . . ............ ...... . . . . . . .... 138 PYOCIN Rl .................................................................................................................. 138 PYOCIN AI'41 .............................................................................................................. 139 MEGACIN A-216 .......................................................................................................... 140 CONCLUDING REMARKS ............. ......................................................................... 140