Mandibulofacial Dysostosis in an African Infant.

her daughter. Most of the descriptions have appeared in the Continental and American literature*. As far as can be ascertained this is the first description of the fully developed syndrome in an African Negro. The salient features of this type of dysostosis are v 1) paipeorai nssures siopmg aownwaras ana laterally('antimongoloid') with a coloboma in the outer portion of the lower lids and, more rarely, in the upper lids; (2) hypoplasia -of the facial bones, especially the malar bones and the mandible; (3) malformation of the external ear and, occasionally, of the middle and inner ears; (4) macrostomia, high palate, abnormal position and malocclusion of the teeth; (5) blind fistulae situated between the angles of the mouth and the