Original Contribution Statin Use and Risk of Prostate Cancer: Results from a Population-based Epidemiologic Study
نویسندگان
چکیده
1 Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA. 2 Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY. 3 Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA. 4 Department of Pharmacy, School of Pharmacy, University of Washington, Seattle, WA. 5 National Human Genome Research Institute, National Institutes of Health, Bethesda, MD.
منابع مشابه
Statin use and risk of prostate cancer: results from a population-based epidemiologic study.
Epidemiologic studies of statin use in relation to prostate cancer risk have been inconclusive. Recent evidence, however, suggests that longer-term use may reduce risk of more advanced disease. The authors conducted a population-based study of 1,001 incident prostate cancer cases diagnosed in 2002-2005 and 942 age-matched controls from King County, Washington, to evaluate risk associated with s...
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Background and Aim: Prostate gland is one of the most important exocrine gland in the male genital system, whose neoplasms are very common in Iran and other countries. The incidence of the disease is not the same among different racial communities. Therefore, epidemiologic studies can be useful in our country. This study was aimed to determine the epidemiologic characteristics of prostate neopl...
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The initial studies of statins and risk of cancer, including prostate cancer, were spurred by concerns of possible increases in incidence among statin users. Such concerns were rapidly dispelled, and indeed reports of an inverse association between prediagnostic statin use and prostate cancer began to appear, although findings were inconsistent and mostly null for overall risk. Platz et al were...
متن کاملCholesterol-lowering drugs and prostate cancer risk: a population-based case-control study.
BACKGROUND Previous studies have shown that statin use may reduce prostate cancer risk. In the current study, we evaluated the association between serum cholesterol-lowering medication use and prostate cancer risk at the population level. MATERIALS AND METHODS All newly diagnosed prostate cancer cases in Finland during 1995 to 2002 and matched controls (24,723 case control pairs) were identif...
متن کاملORIGINAL CONTRIBUTIONS Statins and Prostate Cancer Risk: A Case-Control Study
Observational studies have shown that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (statin) use may be associated with reduced cancer risk. The purpose of this case-control study was to elucidate the association between statin use and prostate cancer risk. Prostate cancer cases (n 1⁄4 100), recruited upon referral for prostate biopsy, and frequency age-matched, prostate-specific an...
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