Supercritical Fluid Extraction+supercritical Fluid Chromatography
نویسنده
چکیده
high pressures also requires special equipment. In summary, both RESS crystallization and SAS crystallization appear to be promising methods for generating supersaturation and therefore represent alternatives to conventional crystallization. Such alternatives may prove attractive in applications such as polymer and pharmaceutical processing, or in particle design for drug delivery. It is possible to obtain a variety of morphologies and particle sizes in these processes by proper choice of conditions and expansion devices. However, a priori design of supercritical crystallization processes is not yet possible because the interaction between phase equilibria, expansion paths, and crystallization kinetics in these processes is not yet well understood.
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