Comparison of DCE-MRI and Dual Echo DSC-MRI Derived Measures of K and ve
نویسندگان
چکیده
Introduction: DSC-MRI data from tumors may be confounded by the extravasation of contrast agent (CA) into the extravascular extracellular space (EES), which results in simultaneous changes in the EES T1 and T2*. It is well known that dual-echo acquisitions can eliminate the T1 leakage effects, but we recently demonstrated that such data, when combined with a pre-contrast T1 map, can also be used to quantify the DCE-MRI parameters, K and ve (1). To further verify this approach we compared DSC-MRI and DCE-MRI derived K and ve values in two brain tumor models with dissimilar perfusion characteristics and contrast agent dynamics.
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