Relationship between blood uric acid level and the onset of acute cerebral infarction

Objective: We discussed the correlation between blood uric acid (BUA) level and the onset of acute cerebral infarction. Method: The measurements of BUA level, blood lipid, blood glucose, and urea and creatinine levels were compared between 640 cases of acute cerebral infarction and 640 healthy cases receiving physical examination. The differences were examined statistically using logistic regression. Result: BUA level of patients with cerebral infarction was higher than that of normal subjects. Correlation analysis indicated that the BUA level was not correlated with age, blood glucose or course of diseases in patients with cerebral infarction; however, it was positively correlated with urea, creatinine, triglyceride and cholesterol, and negatively correlated with length of hospital stay. According to logistic regression analysis, for every increase of BUA level by 1 μmol/L, the risk of acute cerebral infarction decreased by 0.998 time. Conclusion: BUA level of patients with acute cerebral infarction was lower than that in normal subjects; thus BUA level was correlated with the risk of acute cerebral infarction.