The Formation of Doxorubicin Loaded Targeted Nanoparticles using Nanoprecipitation, Double Emulsion and Single Emulsion for Cancer Treatment

Chemotherapeutic agents lead to the damage of healthy cells because they react with cells which are dividing at a high rate by inhibiting the DNA synthesis and interfering with the process of cell division. "Therapeutic drug delivery allows for an increase in the efficacy of the chemotherapeutic agent while minimizing the interaction with nontumour sites in the body by controlling the release rate of the therapeutic agent and having targeted sites on the nanoparticle which will allow the nanoparticle to release its contents at targeted sites." There are three main methods of creating nanocarriers for drug delivery that will be consider in this paper, nanoprecipitation, single emulsion and double emulsion. N Single emulsion is the formation of nanoparticles through oil in water emulsion. Another way to decrease the toxic effect of the drug loaded nanoparticle on the cells is by having specific ligands attached to the nanoparticle that specifically targets a cancer cells or have magnetic particles that one can move to the area where the tumour is located by using a magnet *Corresponding author: Toyin Jibowu, Faculty of Engineering, Chemical and Biochemical Engineering, University of Western Ontario, Canada, Tel: 519-6612131; E-mail: [email protected] Received June 01, 2016; Accepted June 10, 2016; Published June 17, 2016 Citation: Jibowu T (2016) The Formation of Doxorubicin Loaded Targeted Nanoparticles using Nanoprecipitation, Double Emulsion and Single Emulsion for Cancer Treatment. J Nanomed Nanotechnol 7: 379. doi:10.4172/21577439.1000379 Copyright: © 2016 Jibowu T. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.