Alveolar proteinosis in extremis: a critical case treated with whole lung lavage without extracorporeal membrane oxygenation.

Extracorporeal membrane oxygenation to support repeated whole-lung lavage in a patient with pulmonary alveolar proteinosis in life threatening dyspnoe – a case report

BACKGROUD Pulmonary alveolar proteinosis is a rare disorder that is characterized by a large accumulation of lipoproteinaceous material within the alveoli. This causes respiratory failure due to a restriction of gas exchange and changes in the ventilation/perfusion ratio. Clinical symptoms are variable and depend on the severity of damage of the lung parenchyma. Treatment method is whole-lung l...

Combination of extracorporeal membrane oxygenation (ECMO) and pulmonary lavage in a patient with pulmonary alveolar proteinosis.

We describe a rare case of pulmonary alveolar proteinosis in a young woman with dyspnea and progressive hypoxaemia due to the alveolar deposition of insoluble, surfactant-like material. Routine treatment includes whole-lung-lavage (WLL) using double-lumen-tubes for selective lavaging of each lung. We performed three whole-lung-lavages and used veno-venous extracorporeal membrane oxygenation (v-...

Long-term azathioprine therapy in two children with steroid-dependent minimal-change nephrotic syndrome. H. Tanaka, N. Onodera and S. Waga Infantile pulmonary alveolar proteinosis with interstitial pneumonia: Bilateral simultaneous lung lavage utilizing extracorporeal membrane oxygenation and steroid therapy

Respiratory Strategies and Airway Management in Patients with Pulmonary Alveolar Proteinosis: A Review

BACKGROUND Pulmonary alveolar proteinosis is a rare disorder characterized by a large accumulation of lipoproteinaceous material within the alveoli. This causes respiratory failure due to a restriction of gas exchange and changes in the ventilation/perfusion ratio. Treatment methods include noninvasive pharmacological approaches and invasive procedures, such as whole-lung lavage under general a...

Pulmonary Alveolar Proteinosis: A Very Rare Disease and the Role of the Cardiac Surgeon in its Treatment

A 5-year-old boy who had progressive dyspnea of 6 months' duration was found to have pulmonary alveolar proteinosis (PAP) by lung biopsy. PAP is a rare diffuse intra-alveolar lung disease first described by Rosen et al.1 in 1958 and characterized by an accumulation of lipoproteineceous material in the alveoli.2 Bronchoalveolar lavage is considered the best treatment for PAP patients. However, o...