A fast-responsive mitochondria-targeted fluorescent probe detecting endogenous hypochlorite in living RAW 264.7 cells and nude mouse.

نویسندگان

  • Hongde Xiao
  • Kai Xin
  • Haifang Dou
  • Gui Yin
  • Yiwu Quan
  • Ruiyong Wang
چکیده

A very fast-responsive fluorescent probe PZ-Py for imaging mitochondrial HClO/ClO(-), with a relatively long emission wavelength, was prepared. The limit of detection was evaluated to be 17.9 nM. Moreover, the probe PZ-Py was successfully applied in the imaging of endogenous HClO/ClO(-) in the mitochondria of RAW 264.7 cells and living nude mouse.

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عنوان ژورنال:
  • Chemical communications

دوره 51 8  شماره 

صفحات  -

تاریخ انتشار 2015