Sustainable public health systems for rare diseases.

NCD Prevention and Control: Sustainable and Comprehensive Solutions; A Response to Recent Commentaries

Opening the Policy Window to Mobilize Action Against Corruption in the Health Sector; Comment on “We Need to Talk About Corruption in Health Systems”

Corruption in the health sector has been a “dirty secret” in the health policy and international development community, but recent global activities point to a day when it will no longer be neglected as a key determinant of health. To further explore next steps forward, this commentary applies the Kingdon’s multiple-streams framework (MSF) to assess what opportunities are available to mobilize ...

Sustainable rare diseases business and drug access: no time for misconceptions

Legislative incentives enacted in Europe through the Regulation (EC) No. 141/2000 to incentivize orphan drug development have over the last 12 years constituted a powerful impetus toward R&D directed at the rare diseases population. However, despite therapeutic promises contained in these projects and significant economic impact linked to burgeoning R&D expenditures, the affordability and value...

The Need for Global Application of the Accountability for Reasonableness Approach to Support Sustainable Outcomes; Comment on “Expanded HTA: Enhancing Fairness and Legitimacy”

The accountability for reasonableness (AFR) concept has been developed and discussed for over two decades. Its interpretation has been studied in several ways partly guided by the specific settings and the researchers involved. This has again influenced the development of the concept, but not led to universal application. The potential use in health technology assessments (HTAs) has recently be...

Sustainability of Long-term Care: Puzzling Tasks Ahead for Policy-Makers

Background The sustainability of long-term care (LTC) is a prominent policy priority in many Western countries. LTC is one of the most pressing fiscal issues for the growing population of elderly people in the European Union (EU) Member States. Country recommendations regarding LTC are prominent under the EU’s European Semester.   Methods This paper examines challenges related to the financial-...