EcoRI polymorphism in the human third complement component (C3) gene.
نویسندگان
چکیده
Source/Description A cDNA fragment, pC3.11 (1) was used as probe. Polymorphisms: EcoRI cleavage of genomic DNA reveals a 2 allele polymorphism with band sizes of 5.2 and 5.6 kb. Invariant bands of 11.5, 11.0, 9.0 and 3 0 kb were also present. Frequency: Estimated from 35 unrelated Caucasians. Allele Frequency Dl 5.2 0.67 D2 5.6 0.33 Chromosomal Localisation: The human C3 gene had been assigned to chromocome 19 pl3.3-pl3.2 (2). Mendelian Inheritance: Co-dominant inheritance was documented in one family with 8 individuals.
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ورودعنوان ژورنال:
- Nucleic acids research
دوره 18 9 شماره
صفحات -
تاریخ انتشار 1990