George Lyman Duff Memorial Lecture. Atherosclerosis: a problem of the biology of arterial wall cells and their interactions with blood components.
نویسنده
چکیده
I most honored to give the Lyman Duff lecture, since Dr. Duff has had such an impact on atherosclerosis research. As many of you may know, one of Dr. Duff's earliest papers, published in 1932, concerned changes in the rabbit aorta related to medial degeneration produced by diphtheria toxin. His first paper on atherosclerosis was his thesis, written in 1935, in which he looked at "Experimental Cholesterol Arteriosclerosis and its Relationship to Human Arteriosclerosis." Together with Gardner McMillan, he published a paper in 1948 on the inhibition of experimental cholesterol atherosclerosis by Alloxan diabetes in the rabbit. In this paper, they examined the mitogenic activity in the rabbit aorta at a time when most investigators considered atherosclerosis to be an entirely degenerative disease process. Lyman Duff was the Strathcona Professor of Pathology and Dean of the Faculty of Medicine at McGill University. We are still pursuing many of the important questions that were raised by him and his colleagues, and are indebted to them for the foundation they provided in research. In this lecture, I should like to raise a series of questions concerning the role played by each of the cells of the blood and of the artery wall as
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ورودعنوان ژورنال:
- Arteriosclerosis
دوره 1 5 شماره
صفحات -
تاریخ انتشار 1981