Radical deoxygenation of hydroxyl groups via phosphites.
نویسندگان
چکیده
A highly efficient, two-step sequence method for the deoxygenation of hydroxyl groups has been developed. The method involves the preparation of the 2-(2-iodophenyl)ethyl methyl phosphite derivative of an alcohol using methyl dichlorophosphite and 2-(2-iodophenyl)ethanol. Treatment of the phosphite intermediate with (n-Bu)3SnH/AIBN in refluxing benzene cleanly produces the deoxygenation product of the original alcohol.
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 126 41 شماره
صفحات -
تاریخ انتشار 2004