Antibody Response and Disease Severity in Healthcare Worker MERS Survivors.
نویسندگان
چکیده
We studied antibody response in 9 healthcare workers in Jeddah, Saudi Arabia, who survived Middle East respiratory syndrome, by using serial ELISA and indirect immunofluorescence assay testing. Among patients who had experienced severe pneumonia, antibody was detected for >18 months after infection. Antibody longevity was more variable in patients who had experienced milder disease.
منابع مشابه
Recovery from the Middle East respiratory syndrome is associated with antibody and T-cell responses.
The Middle East respiratory syndrome coronavirus (MERS-CoV) causes a highly lethal pneumonia. MERS was recently identified as a candidate for vaccine development, but most efforts focus on antibody responses, which are often transient after CoV infections. CoV-specific T cells are generally long-lived, but the virus-specific T cell response has not been addressed in MERS patients. We obtained p...
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ورودعنوان ژورنال:
- Emerging infectious diseases
دوره 22 6 شماره
صفحات -
تاریخ انتشار 2016