Nitrone-mediated radical coupling reactions: a new synthetic tool exemplified on dendrimer synthesis.
نویسندگان
چکیده
A synthetic strategy employing nitrones as radical spin traps is presented on the example of the efficient generation of novel dendrimers via a combination of radical and classical 'click' chemistry.
منابع مشابه
Reductive Coupling Reactions of Nitrones and Imines, Modern Versions
INTRODUCTION Pinacol coupling was first described by Fittig in 1859, when he reported the formation of 2,3dimethyl-2,3-butanediol (1) from acetone and sodium metal. Since then, this ketyl radical anion coupling process has undergone significant advancement, including the development of asymmetric variants. 3 Alternatives to use of strong reducing metals are low valent transition metals and lant...
متن کاملChem. Pharm. Bull. 53(8) 995—1002 (2005)
ways for carbon–carbon bond formation in organic synthesis. In particular, radical-mediated cyclization has been developed as a potential method for preparing various types of cyclic compounds via intramolecular carbon–carbon bond-forming processes. We have recently developed a new efficient carbon–carbon bond-forming reaction based on sulfanyl, stannyl and alkyl radical addition-cyclization (C...
متن کاملTitanocene(III) chloride mediated radical-induced opening of monosubstituted epoxy acetates for the synthesis of primary allylic alcohols
The radical chemistry has become an inevitable tool to the organic chemists now a days for the formation of carbon-carbon bonds. Prolific use of this particular field of chemistry is well established and growing continuously for the synthesis of carbocyclic as well as heterocyclic natural products. High stereo-and regioselectivity and mildness of the radical technique unaffecting various sensit...
متن کاملSynthetic Application of Magnetic Nanocomposite Fe3O4@PEG-Au as a Heterogeneous and Reusable Nanocatalyst in The Suzuki Coupling Reactions
In the present study, we carried out chemical synthesis and characterization of Fe3O4@PEG-Au as a magnetic nanocomposite in aqueous solution by chemical co-precipitation of Fe3+ and Fe2+ ions and encapsulated by poly (ethylene glycol) (PEG) in order to enhancing hydrophilicity, biocompatibility and immobilizing gold ions in the presence of NaBH4 as a reducing agent. Nanostructures were characte...
متن کاملNitroxide-Mediated Radical Polymerization of Styrene Initiated from the Surface of Titanium Oxide Nanoparticles
Titanium dioxide (TiO2) nanoparticles, with an average size of about 45 nm, were encapsulated by polystyrene using in situ nitroxide mediated radical polymerization in the presence of 3-aminopropyl triethoxy silane (APTES) as a coupling agent and 2, 2, 6, 6-tetramethylpiperidinyl-1-oxy as a initiator. First, the initiator for NMRP was covalently bonded onto the surface of Titanium dioxide na...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 47 19 شماره
صفحات -
تاریخ انتشار 2011