Paroxetine and sertraline delayed ejaculation in heterosexual men with lifelong rapid ejaculation.
نویسنده
چکیده
Patients 48 heterosexual men (mean age 39 y) who had lifelong rapid ejaculation and a stable relationship with a female partner. Rapid ejaculation was defined as an intravaginal ejaculation latency time (IELT) of <1 minute. Exclusion criteria included erectile dysfunction, alcohol or substance abuse, mental disorders, physical illnesses, and concomitant medications. 83% of patients completed the study.
منابع مشابه
Selective serotonin-reuptake inhibitors in the treatment of premature ejaculation.
OBJECTIVE To review the use of selective serotonin-reuptake inhibitors (SSRIs) in the treatment of premature ejaculation. DATA SOURCES Articles were retrieved through a MEDLINE search (1966-January 2004). Search terms used to identify articles included serotonin uptake inhibitors, premature ejaculation, rapid ejaculation, and sexual behavior, as well as the generic names of currently availabl...
متن کاملSerotonin Transporter Promoter Region (5-HTTLPR) Polymorphism Is Not Associated With Paroxetine-Induced Ejaculation Delay in Dutch Men With Lifelong Premature Ejaculation
PURPOSE To investigate the association between the 5-HT-transporter-gene-linked promoter region (5-HTTLPR) polymorphism and 20-mg paroxetine-induced ejaculation delay in men with lifelong premature ejaculation (LPE). MATERIALS AND METHODS This was a prospective study of 10 weeks of paroxetine treatment in 54 men with LPE. Intravaginal ejaculation latency time (IELT) was measured by stopwatch....
متن کاملNonresponders to Daily Paroxetine and Another SSRI in Men With Lifelong Premature Ejaculation: A Pharmacokinetic Dose-Escalation Study for a Rare Phenomenon
PURPOSE Nonresponse to any selective serotonin reuptake inhibitor (SSRI) treatment is rare. In this study, we aimed to investigate ejaculation delay nonresponse to paroxetine treatment in men with lifelong premature ejaculation (PE) who were also known to be nonresponders to other SSRIs. MATERIALS AND METHODS Five males with lifelong PE who were known nonresponders to paroxetine and other ser...
متن کاملClinical inquiries. What's the best drug treatment for premature ejaculation?
antidepressants—specifically clomipramine, fluoxetine, paroxetine, and sertraline—are best and have been shown to improve symptoms of premature ejaculation (strength of recommendation [sor]: a, meta-analysis of randomized controlled trials [rcTs]). The topical application of prilocaine-lidocaine cream (trade name eMla) improves intravaginal ejaculatory latency time (IelT), but penile numbness a...
متن کاملThe pharmacological treatment of premature ejaculation.
Premature ejaculation (PE) is a common sexual dysfunction in men that is characterized by a short time to ejaculation, and a lack of control over ejaculation, and is associated with distress for men and their partners. Lack of knowledge about the aetiology of PE and lack of approved treatments might contribute to its under-diagnosis and under-treatment. The organic factors involved in PE are no...
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ورودعنوان ژورنال:
- Evidence-based mental health
دوره 5 1 شماره
صفحات -
تاریخ انتشار 2002