ACE inhibitors and AT(1) receptor antagonists-beyond the haemodynamic effect.

and this was associated with increased expression of The classical view of angiotensin II (Ang II ) as a mRNA of extracellular matrix proteins and matrix vasoactive agent that participates in local and systemic deposition. These abnormalities were reduced by ACE haemodynamic regulation has been recently enlarged inhibition and 1 receptor blockade [5,6,12]. to consider it as a true cytokine with an active role in