Total synthesis of ceratopicanol through tandem cycloaddition reaction of a linear substrate.

نویسندگان

  • Sang-Shin Lee
  • Won-Yeob Kim
  • Hee-Yoon Lee
چکیده

Total synthesis of ceratopicanol (1) was achieved with a tandem cycloaddition reaction of allenyl diazo compound 6 via a trimethylenemethane (TMM) diyl intermediate. The TMM diyl mediated [2+3] cycloaddition reaction furnished the consecutive quaternary carbon centers and showed an unusual diastereoselectivity.

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عنوان ژورنال:
  • Chemistry, an Asian journal

دوره 7 10  شماره 

صفحات  -

تاریخ انتشار 2012