A flexible method for fabrication of nerve cuff electrodes
نویسنده
چکیده
Ahstruct A method for construction of cuff electrodes is presented. The method is based on using platinum foil electrodes fixed by rubber bands on a Teflon coated mandrel, that is then dip-coated with silicone. The method allows for design of cuff electrodes of practically any size, shape and electrode configuration, and simple cuffs can be built in less than one hour of work Cuff electrodes have been built that range in size from 0.5 to 10 mm ID and 5 to 70 mm length and number of electrodes from one to twelve. Tri-polar recording electrodes have been tested in more than 30 chronic implantations in rabbits (tibial nerve) and for various acute experiments, where different electrode configurations were investigated. None of the chronic implants have failed and impedances have been stable for one year.
منابع مشابه
Cuff electrodes for chronic stimulation and recording of peripheral nerve activity.
A comparative study of 5 different designs of nerve cuff electrodes was undertaken to determine their relative merits for stimulating and recording whole-nerve activity over extended periods of chronic implantation on large and small peripheral nerves in 8 cats. Four of the designs represent novel fabrication strategies, including 2 based on flexible, thin-film substrates and 2 based on dip-coa...
متن کاملMicromachined Multichannel Cuff ' Electrodes for Interfacing Small Nerves
Cuff electrodes are often used for interfacing nerves. Especially for small nerves, a new approach of flexible and light-weighted multichannel cuff electrodes with integrated cables has been developed using micro-chining technologies. Here, the process technology is shortly introduced. The results of in vitro test were discussed. In vivo implantations showed excellent properties of the electrod...
متن کاملDevelopment of double-sided multi-channel microelectrodes for a vestibular prosthesis
Vestibular prostheses aim at substituting lost vestibular function by stimulating the vestibulocochlear nerve. For this purpose, suitable microelectrode structures have to be developed, making high demands on fabrication technology. Flexible, polyimide-based systems can be used for this purpose, however in order to insert such electrodes in the semicircular canals in the ear, adequate stiffness...
متن کاملIn vivo assessment of tissue compatibility and functionality of a polyimide cuff electrode for recording afferent peripheral nerve signals
Minimally-invasively implantable spiral cuff electrodes coated with polyimide (PI) for insulation in combination with suitably designed amplifiers were recently reported to allow signalling of electroneurograms (ENGs). These cuff electrodes can be used to record the respiratory drive after implantation on the phrenic nerve, but PI can cause epineurial fibrosis, fiber loss, and limited reproduci...
متن کاملNerve Cuff Electrodes for Prosthetic and Research Applications
A new generation of nerve cuffs suitable for stimulation, recording and modulation of nerve activity has been tested in our laboratory and elsewhere. The walls are molded of low-durometer silicone and incorporate flexible electrodes, Teflon-coated stainless steel leads and an interlocking opening/closing system. Stimulation and recording cuffs can be either single-channel or multichannel. Singl...
متن کامل