Reduced functional brain activity response in cognitively intact apolipoprotein E «4 carriers
نویسندگان
چکیده
Department of Clinical Neuroscience, MR Research Center, Karolinska Hospital N-8, Stockholm Aging Research Center, Department of Psychology, Stockholm University, Stockholm, Department of Psychology, Department of Radiation Sciences, Clinical Sciences and Psychiatry, Umeå University, Umeå, Sweden and Department of Molecular Genetics, Flanders Interuniversity Institute for Biotechnology, University of Antwerp, Antwerpen, Belgium
منابع مشابه
From the DEPARTMENT OF CLINICAL NEUROSCIENCE Karolinska Institutet, Stockholm, Sweden MEMORY, GENES, AND BRAIN IMAGING: RELATING THE APOE GENE TO BRAIN FUNCTION AND STRUCTURE
Alzheimer’s disease (AD) is the most common form of dementia. An important goal for current AD research is to find preclinical markers of impending disease. Apolipoprotein E ε4 (APOE ε4) is the chief known genetic risk factor for AD. A number of neuroimaging studies have reported structural and functional brain alterations in non-demented APOE ε4-carriers. Such results have tentatively been int...
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