[Neurotrophic keratitis].

Neurotrophic keratitis in a patient with disseminated lymphangiomatosis.

INTRODUCTION Neurotrophic keratitis, a degenerative corneal disease caused by trigeminal nerve impairment, has many etiologies and remains very difficult to treat. METHODS Case report of a 23-year-old male with a right corneal ulcer that failed to improve despite broad-spectrum antimicrobials. RESULTS Prior diagnosis of disseminated lymphangiomatosis with a lesion in the right petrous apex ...

Neurotrophic factors and corneal nerve regeneration

The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination. Corneal sensitivity is provided by the ophthalmic branch of the trigeminal nerve that elicits protective reflexes such as blinking and tearing and exerts trophic supp...

Bilateral herpetic keratitis presenting with unilateral neurotrophic keratitis in pemphigus foliaceus: a case report

INTRODUCTION We report a case of bilateral herpetic keratitis developing after rapid oral corticosteroid tapering in a patient with pemphigus foliaceus, which was followed by unilateral neurotrophic keratitis that was treated with amniotic membrane transplantation. CASE PRESENTATION A 71-year-old Korean man developed bilateral herpetic keratitis one week after rapid tapering of systemic corti...

Neurotrophic keratitis presenting in infancy with involvement of the motor component of the trigeminal nerve.

Pigmented conjunctival lesions as initial manifestation of ochronosis.

tients are at risk for lagophthalmos and exposure-related keratitis. The post-LASIK neurotrophic status of these patients may further predispose them to infectious keratitis. The first case represents, to our knowledge, the earliest postLASIK human histopathologic finding (9 days post-LASIK). The neurotrophic cornea would certainly be a risk factor in the immediate postoperative period. The fir...

Application of umbilical cord serum eyedrops for the treatment of neurotrophic keratitis.

PURPOSE To investigate the efficacy of umbilical cord serum eyedrops for the treatment of neurotrophic keratitis. DESIGN Prospective noncomparative case series. PARTICIPANTS Twenty-eight eyes of 28 patients with neurotrophic keratitis who were refractory to conventional treatment. METHODS The patients with neurotrophic keraitis were treated with 20% umbilical cord serum eyedrops 6 to 10 t...